← All awesome lists Search these repos

Awesome List

Awesome Bioinformatics

A curated list of awesome Bioinformatics libraries and software.

danielecook/Awesome-Bioinformatics #awesome #awesome-list #bioinformatics

Open GitHub

List stars: 4,329
README repos: 132
Indexed repos: 127
List commits: 273
Forks: 742
Open issues: 46

Tracked list growth

GitHub stars and default-branch commits for danielecook/Awesome-Bioinformatics.

Latest scan 2026-10-22 10:49

Likes history

GitHub stars

Commits history

Default branch commits

Indexed repositories

16 repos matching these filters.

Package manager: cmake

Latest repo push 2026-10-22

Browse

Filter this list

Search within Awesome Bioinformatics or narrow by ecosystem and project health.

Clear 1 refinement

Search repositories

Search mode

Keyword Semantic

Tune results

The controls most people need first.

Language

Freshness

Sort

Direction

More filters Topics, generated tags, stack, files, age, archive status, and growth.

Ecosystem

GitHub topic

Generated tag

Framework or stack

Package manager

Files

Has file

Choose a suggestion or use commas to require multiple files.

Health

Minimum stars

Repository age

Uses known first-commit dates.

Archive status

AI development signals

Momentum

Unmaintained for

Commit velocity

Star growth

Reset filters

Highlighted

Open highlighted repo slot

Put your repository first

Promote a GitHub repo at the top of Awesome repository list views for 7 days.

soedinglab/MMseqs2

MMseqs2: ultra fast and sensitive search and clustering suite

Stack

C Cargo CMake .NET SDK

GitHub topics

#alignment #bioinformatics #blast #linclust #metagenomics #mmseqs

Updated: 2026-10-20
Lists: 1 list mention
First commit: 2012-12-17
License: MIT
Issues: 296 open

2,156

stars

Forks: 311
Commits: 6,851 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

Website GitHub

bbuchfink/diamond

Accelerated BLAST compatible local sequence aligner.

Stack

C++ CMake

GitHub topics

#sequence-alignment

Updated: 2026-10-21
Lists: 1 list mention
First commit: 2015-03-10
License: GPL-3.0
Issues: 218 open

1,330

stars

Forks: 205
Commits: 2,239 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

ablab/spades

SPAdes Genome Assembler

Stack

C++ CMake

GitHub topics

#genome-assembly #illumina #metagenome-assembly #next-generation-sequencing #sequence-assembler #sequencing

Updated: 2026-10-05
Lists: 1 list mention
First commit: 2011-01-24
License: NOASSERTION
Issues: 305 open

967

stars

Forks: 166
Commits: 15,362 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

Website GitHub

BenLangmead/bowtie2

A fast and sensitive gapped read aligner

Stack

C++ CMake

GitHub topics

#bioinformatics #c-plus-plus #genomics #read-aligners

Updated: 2026-09-22
Lists: 1 list mention
First commit: 2011-03-12
License: GPL-3.0
Issues: 197 open

811

stars

Forks: 180
Commits: 2,682 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

vcflib/vcflib

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings

Stack

C++ CMake

GitHub topics

#genomics #genotyping #haplotypecaller #variant-calling #vcf-manipulation

Updated: 2026-10-02
Lists: 1 list mention
First commit: 2010-09-22
License: MIT
Issues: 17 open

687

stars

Forks: 223
Commits: 1,699 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

Website GitHub

mattgodbolt/zindex

Create an index on a compressed text file

Stack

C++ CMake

Updated: 2026-10-20
Lists: 1 list mention
First commit: 2015-02-23
License: BSD-2-Clause
Issues: 19 open

658

stars

Forks: 39
Commits: 213 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

Illumina/manta

Structural variant and indel caller for mapped sequencing data

Archived

Stack

C++ CMake

GitHub topics

#bioinformatics #indels #structural-variation #structural-variations

Updated: 2025-10-11
Lists: 1 list mention
First commit: 2013-05-30
License: NOASSERTION
Issues: 130 open

467

stars

Forks: 160
Commits: 2,634 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

seqan/seqan3

The modern C++ library for sequence analysis. Contains version 3 of the library and API docs.

Stack

C++ CMake

GitHub topics

#bioinformatics #blast #cpp-concepts #cpp20 #fasta #fastq

Updated: 2026-10-17
Lists: 1 list mention
First commit: 2017-03-17
License: NOASSERTION
Issues: 33 open

465

stars

Forks: 89
Commits: 7,116 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

Website GitHub

brentp/cyvcf2

cython + htslib == fast VCF and BCF processing

Stack

Cython CMake PEP 517 pip

GitHub topics

#bioinformatics #cython #genomics #htslib #vcf

Updated: 2026-09-10
Lists: 1 list mention
First commit: 2015-08-12
License: MIT
Issues: 51 open

450

stars

Forks: 79
Commits: 552 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

pezmaster31/bamtools

C++ API & command-line toolkit for working with BAM data

Stack

C++ CMake

Updated: 2025-05-18
Lists: 1 list mention
First commit: 2009-04-10
License: MIT
Issues: 72 open

432

stars

Forks: 154
Commits: 519 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

arq5x/lumpy-sv

lumpy: a general probabilistic framework for structural variant discovery

Stack

C CMake

Updated: 2026-02-22
Lists: 1 list mention
First commit: 2012-10-08
License: MIT
Issues: 197 open

346

stars

Forks: 116
Commits: 575 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

luntergroup/octopus

Bayesian haplotype-based mutation calling

Stack

C++ React CMake npm

GitHub topics

#bioinformatics #de-novo-mutation #genomics #haplotypes #phasing #single-cell

Updated: 2026-02-13
Lists: 1 list mention
First commit: 2015-02-04
License: MIT
Issues: 65 open

327

stars

Forks: 37
Commits: 5,045 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

jeffdaily/parasail

Pairwise Sequence Alignment Library

Stack

C CMake Meson

Updated: 2025-08-27
Lists: 1 list mention
First commit: 2014-09-23
License: NOASSERTION
Issues: 34 open

289

stars

Forks: 44
Commits: 1,277 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

Marco-Sola-Lab/WFA2-lib

WFA-lib: Wavefront alignment algorithm library v2

Stack

C CMake

Updated: 2026-10-16
Lists: 1 list mention
First commit: 2021-06-13
License: NOASSERTION
Issues: 19 open

231

stars

Forks: 56
Commits: 300 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

dnanexus-rnd/GLnexus

Scalable gVCF merging and joint variant calling for population sequencing projects

Stack

C++ CMake

Updated: 2024-04-12
Lists: 1 list mention
First commit: 2015-04-08
License: Apache-2.0
Issues: 103 open

190

stars

Forks: 53
Commits: 642 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

TimoLassmann/samstat

SAMStat displays various properties of next-generation sequencing reads stored in SAM/BAM format.

Stack

C CMake

GitHub topics

#bioinformatics #next-generation-sequencing #quality-control

Updated: 2026-10-21
Lists: 1 list mention
First commit: 2014-06-12
License: NOASSERTION
Issues: 1 open

stars

Forks: 6
Commits: 354 commits
Star growth, last 7 days: 0 0.0%
Commit velocity, last 7 days: 0 0.0%

GitHub

Activity

Default branch: master
Last pushed: 2026-09-27
GitHub updated: 2026-10-21
Created: 2014-08-27
First commit: 2014-08-27
Last scanned: 2026-10-22 10:49
Watchers: 168

Indexed repo mix

Repo stars: 91,693
Repo forks: 21,493
Active: 121
Archived: 6

Languages

Python (32) C++ (21) C (19) Java (9) Go (7) JavaScript (7) Perl (4) Nextflow (3) Nim (3) Cython (2) Groovy (2) HTML (2)

Awesome Bioinformatics

Tracked list growth

Likes history

Commits history

Indexed repositories

Filter this list

Put your repository first

How it works

Pricing